Ca2+-Dependent Metarhodopsin Inactivation Mediated by Calmodulin and NINAC Myosin III
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Ca2+-Dependent Metarhodopsin Inactivation Mediated by Calmodulin and NINAC Myosin III
Phototransduction in flies is the fastest known G protein-coupled signaling cascade, but how this performance is achieved remains unclear. Here, we investigate the mechanism and role of rhodopsin inactivation. We determined the lifetime of activated rhodopsin (metarhodopsin = M( *)) in whole-cell recordings from Drosophila photoreceptors by measuring the time window within which inactivating M(...
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ژورنال
عنوان ژورنال: Neuron
سال: 2008
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2008.07.007